Objective To investigate the salt taste sensitivity and its influencing factors in patients with chronic kidney disease（CKD）,for promoting the implementation of salt restriction dietary treatment.Methods Totally 625 CKD patients were recruited during December,2014 and March,2017 at three renal medical wards in a tertiary hospital in Hangzhou. The salt threshold measurement was used to assess salt taste sensitivity. Patient information on social demographic characteristics,disease status and previous salt restriction behaviors were collected to explore influencing factors.Results The average salt threshold was（0.34±0.22）%,and the number of patients with low（<0.2%）,medium（0.2%~0.4%）,and high salt threshold（>0.4%） were 67（10.7%）,433（69.3%） and 125（20.0%）,respectively. Multivariate logistic regression revealed that groups with a higher salt threshold were as follows：gender（male）,older age,previous absence of salt restriction behaviors,decreased eGFR. Conclusion The salt threshold in CKD patients was higher than normal individuals. The salt threshold of patients should be taken into account in clinical guidance of salt restriction. Individualized salt restriction should be adopted for patients with different age,gender,and renal function,especially for patients with high salt threshold.